AC-LEHD-PNA

Uses

Caspase 9 is an initiator caspase th at cleaves procaspase 3 and procaspase 7 to propagate the apoptotic cascade. Caspase 9 may be detected using a variety of chromogenic and fluorogenic peptide substrates built around the LEHD peptide core such as the chromogenic substrate Ac-LEHD-pNa (Ac-Leu-Glu-His-Asp-p-nitroanalide).

Biological Activity

Cell permeable: no', 'Primary Target
Caspase-9', 'Product does not compete with ATP.', 'Reversible: no