Uses
3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 μM, an Ki value of 0.58 μM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies[1].
References
[1] YichaoGe， et al. Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches. European Journal of Medicinal Chemistry, 2022, 114699.
[2] THERESA FUK NING KWONG. Novel Antifouling and Antimicrobial Compound from a Marine-Derived Fungus Ampelomyces sp.[J]. Marine Biotechnology, 2006, 8 6: 634-640. DOI:
10.1007/s10126-005-6146-2[3] YONG LI. New radical scavenging and ultraviolet-A protecting prenylated dioxopiperazine alkaloid related to isoechinulin A from a marine isolate of the fungus Aspergillus.[J]. Journal of Antibiotics, 2004, 57 5: 337-340. DOI:
10.7164/antibiotics.57.337[4] YANJUN ZHANG. 3-Chloro-2,5-dihydroxybenzyl alcohol activates human cervical carcinoma HeLa cell apoptosis by inducing DNA damage.[J]. International journal of oncology, 2007, 31 6: 1317-1323.
