Description
Amino-Tri-(carboxyethoxymethyl)-methane is a branched molecule that is reactive towards carboxylic acids in the presence of HATU. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Biological Activity
Amino-Tri-(carboxyethoxymethyl)-methan is a cleavable PEG-based ADC linker that can be used to synthesize antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
