4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate monohydrochloride

SSR180711 hydrochloride rapidly penetrates into the brain (ID₅₀=8?mg/kg; p.o.). SSR180711 hydrochloride dose-dependently inhibits the specific [^3H]α-BTX binding in the mouse brain (ID₅₀=8.3 and 7.5?mg/kg for p.o. and i.p., respectively)^[1].
SSR180711 hydrochloride (1-10?mg/kg for i.p.; 10-30 mg/kg for p.o.) dose-dependently increases extracellular acetylcholine (ACh) levels in the hippocampus and prefrontal cortex of freely moving rats^[1].
SSR180711 hydrochloride (0.1, 0.3, 1?mg/kg; i.v.) dose-dependently increases firing rate^[1].