Description
N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.
Uses
Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.
