Uses
VU0155056 has been used as a phospholipase D-1 (PLD1) inhibitor:
- to study its role in regulated exocytosis
- to test bacterial and human PLD enzymes for specificity of inhibition
- in neuro-2a (N2a) cell culture and survival assay
Definition
ChEBI: N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide is a naphthalenecarboxamide.
Biological Activity
VU0155056 or N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl ethyl)-2-naphthamide is a cell permeable phospholipase D (PLD) inhibitor. It inhibits both PLD1 and PLD2.
![N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthaMide Structure](https://www.chemicalbook.com/CAS/20150408/GIF/1130067-18-3.gif)
