Uses
2′-Deoxyadenosine 5′-triphosphate (dATP) is used as a substrate by a variety of polymerases including DNA polymerase(s) and reverse transcriptase(s).
Uses
2′-Deoxyadenosine 5′-triphosphate disodium salt
- for Smac- X-linked inhibitor of apoptosis protein (Smac-XIAP) binding assay
- as a component of polymerase chain reaction (PCR) using AM-toxin primers
- to determine the affinity constant (Kd) with the transcription termination factor Rho
Biological Activity
Deoxyadenosine-5-triphosphate (dATP) plays a major role in the initiation of apoptosis in vitro. dATP is considered as an inhibitor of mammalian ribonucleotide reductase, thereby DNA synthesis.
