COP-1
- Product NameCOP-1
- CAS28704-27-0
- CBNumberCB2151979
- MFC23H41N5O11
- MW563.61
- MDL NumberMFCD00166401
- MOL File28704-27-0.mol
COP-1 Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Sigma-Aldrich P1152 | 10mg | $97.2 | Poly(Ala, Glu, Lys, Tyr) 6:2:5:1 hydrobromide
Ala:Glu:Lys:Tyr (6:2:5:1), mol wt 20,000-30,000 |
Buy |
Sigma-Aldrich P1152 | 25mg | $490 | Poly(Ala, Glu, Lys, Tyr) 6:2:5:1 hydrobromide
Ala:Glu:Lys:Tyr (6:2:5:1), mol wt 20,000-30,000 |
Buy |
American Custom Chemicals Corporation API0015275 | 5MG | $505.37 | GLATIRAMER 95.00% |
Buy |
COP-1 Chemical Properties,Usage,Production
Description
Copaxone was launched in Israel and the US for treatment of relapsingremitting multiple sclerosis. The amino acid polymer is prepared from the Ncarboxyanhydrides of Tyr, Ala, γ-benzylglutamate and ε,N-trifluoroacetyllysine followed by deprotection. Structurally, the random polymer, with a residue molar ratio of 6.0:1.9:4.7:1.O=Ala:Glu:Lys:Tyr, simulates myelin basic protein (MBP). This gives it immunomodulating and immunosuppressive activity (antigen specific so not a general immunosuppressive). The mechanism involves binding to MHC class Ⅱ (I-A/DR) molecules which results both in competition with myelin antigens for T-cell activation and in induction of specific suppressor cells of the Th2 type. Therefore, the antigenspecific interaction gives rise to a reduced probability of long-term damage to the immune system. The competition with MBP and other myelin-associated antigens inhibits T-cell responses to MBP, and the binding occurs with high efficiency, fast rates and is non-species specific. It resulted in a 29% reduction in relapse rate and is most effective in patients with less accumulated neurologic disability.Originator
Yeda (Israel)brand name
CopaxonePreparation Products And Raw materials
COP-1 Suppliers
Global(18)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
+16313385890 | info@protheragen-ing.com | United States | 1091 | 58 | |
+1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 | |
+8613063595538 | donboo@donboo.com | China | 9365 | 58 | |
025-025-58361106-805-805 13082558573 |
liugang@njpeptide.com | China | 9978 | 55 | |
021-58432009 400-005-6266 |
marketing@energy-chemical.com | China | 44941 | 58 | |
18902340307 18902340307 |
3356812514@qq.com | China | 9249 | 58 | |
18168071971 | support@yuan-peptide.com | China | 2978 | 58 | |
18696113233 | 15927219311@163.com | China | 1616 | 58 | |
17362916295; 17362916295 |
w17362916295@163.com | China | 4054 | 58 | |
0571-88211951 13735575465 |
sales1@gotopbio.com | China | 4904 | 58 |
28704-27-0, COP-1Related Search
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
- Cupric acetylacetonate
- COBALT(II) ACETYLACETONATE
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
- Aluminum acetylacetonate
1of4
PROMPT×
PROMPT
The What'sApp is temporarily not supported in mainland China
The What'sApp is temporarily not supported in mainland China
Cancel
Determine