Chemical Properties
Pale Yellow Powder
Uses
Sanguinine has a more potent acetylcholinesterase inhibitory activity than galanthamine due to an extra hydroxyl group available for potential interaction with acetylcholinesterase. Sanguinine, in turn, is 10-fold more selective than galanthamine for acetylcholinesterase (AChE) vs. butyrylcholinesterase (BuChE). The lack of AChE inhibitory activity of lycoramine and epinorlicoramine could be due to the occurrence of a double bond in ring C, which does not allow these alkaloids to have the same spatial configuration as the active alkaloids of this series.
Uses
A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor.
Uses
A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor
Definition
ChEBI: Sanguinine is a benzazepine.
