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Pregnenolone

Pregnenolone Structure
Pregnenolone
  • CAS No.145-13-1
  • Chemical Name:Pregnenolone
  • CBNumber:CB1684326
  • Molecular Formula:C21H32O2
  • Formula Weight:316.48
  • MOL File:145-13-1.mol
Pregnenolone Property
  • Melting point: :188-190 °C
  • alpha  :28.5 º (c=1, EtOH)
  • Boiling point: :395.89°C (rough estimate)
  • Density  :1.0382 (rough estimate)
  • refractive index  :1.5344 (estimate)
  • Flash point: :9℃
  • storage temp.  :Refrigerator
  • solubility  :ethanol: soluble10mg/mL, clear, colorless to faintly yellow
  • form  :Powder
  • pka :15.00±0.70(Predicted)
  • color  :White to off-white
  • Water Solubility  :41mg/L(room temperature)
  • Merck  :7733
  • BRN  :2059026
  • InChIKey :ORNBQBCIOKFOEO-QGVNFLHTSA-N
  • CAS DataBase Reference :145-13-1(CAS DataBase Reference)
  • EWG's Food Scores :1
  • FDA UNII :73R90F7MQ8
  • NIST Chemistry Reference :Pregnenolone(145-13-1)
Safety
  • Safety Statements  :22-24/25
  • RIDADR  :UN 1648 3 / PGII
  • WGK Germany  :3
  • RTECS  :TU5560700
  • HS Code  :29372900
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H302+H312+H332-H319
  • Precautionary statements P210-P280-P305+P351+P338
Pregnenolone Price More Price(9)
  • Brand: Sigma-Aldrich
  • Product number: P9129
  • Product name : 5-Pregnen-3β-ol-20-one
  • Purity: ≥98%
  • Packaging: 1g
  • Price: $39.6
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: P-104
  • Product name : 5-Pregnen-3β-ol-20-one
  • Purity: 100 μg/mL in acetonitrile, certified reference material
  • Packaging: 104-1ml
  • Price: $51.6
  • Updated: 2019/12/02
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 19864
  • Product name : Pregnenolone
  • Purity: ≥98%
  • Packaging: 500mg
  • Price: $25
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 19864
  • Product name : Pregnenolone
  • Purity: ≥98%
  • Packaging: 1g
  • Price: $32
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: P9129
  • Product name : 5-Pregnen-3β-ol-20-one
  • Purity: ≥98%
  • Packaging: 5g
  • Price: $54.2
  • Updated: 2019/12/02
  • Buy: Buy

Pregnenolone Chemical Properties,Usage,Production

  • Description Pregnenolone serves as the common precursor in the formation of the adrenocorticoids and other steroid hormones. This C21 steroid is converted via enzymatic oxidations and isomerization of the double bond to a number of physiologically active C21 steroids, including the female sex hormone progesterone and the adrenocorticoids hydrocortisone (cortisol), corticosterone, and aldosterone. Oxidative cleavage of the two-carbon side chain of pregnenolone and subsequent enzymatic oxidations and isomerization lead to C19 steroids, including the androgens testosterone and dihydrotestosterone. The final group of steroids, the C18 female sex hormones, are derived from oxidative aromatization of the A ring of androgens to produce estrogens.
  • Chemical Properties white to off-white powder
  • Uses glucocortcoid, antiinflammatory
  • Uses Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA an tagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A
  • Definition ChEBI: A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20.
Pregnenolone Preparation Products And Raw materials
Raw materials
Preparation Products
Global(342)Suppliers
  • Supplier:
    Henan Tianfu Chemical Co.,Ltd.
  • Tel:0371-55170693
  • Fax:0371-55170693
  • Email:info@tianfuchem.com
  • Country:CHINA
  • ProdList:22625
  • Advantage:55
  • Supplier:
    career henan chemical co
  • Tel:+86-371-86658258
  • Fax:
  • Email:sales@coreychem.com
  • Country:CHINA
  • ProdList:30043
  • Advantage:58
145-13-1, PregnenoloneRelated Search:
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  • 1-((3S,8S,9S,10R,13S,14S,17S)-3-HYDROXY-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)-ETHANONE
  • (3-beta)-pregn-5-en-20-on
  • 3-beta-hydroxy-pregn-5-en-20-on
  • 5-pregnen-3B-ol-20-one
  • 5-pregnen-3β-ol-20-one
  • 1-[(3S,8S,9S,10R,13S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
  • 3β-hydroxy-pregn-5-ene-20-one
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  • 3Hydroxy-5-Pregnen-20-one
  • 3β-Hydroxypregn-5-en-20-one
  • -20-one
  • 5-Preg
  • nen-3β-oL
  • PREGNENOLONE(3BETA-HYDROXYPREGN-5-EN-20-ONE)
  • Progeserone
  • PREGNENOLONE(RG)
  • 145-13-1
  • 145-31-1
  • C21H32O2
  • Complex Molecules
  • BioChemical
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Lipid Library
  • Metabolic Libraries
  • Metabolomics
  • Steroids (Others)
  • Steroids
  • Hydroxyketosteroids
  • Intermediates & Fine Chemicals