Pregn-5-en-3-ol,(3)-(9CI)

Uses

Pregn-5-en-3β-ol, a steroid compound, when formulated as the biscarboxylic acid hemiesters along with androst-5-en-3β-ol, serves as a potent positive allosteric modulator of NMDA (N-methyl-D-aspartate) receptors, making it applicable for research into psychiatric disorders[1].

Definition

ChEBI: 3beta-Hydroxypregn-5-ene is a corticosteroid hormone.

References

[1] Marika Matousova, et al. Pregn-5-en-3β-ol and androst-5-en-3β-ol dicarboxylic acid esters as potential therapeutics for NMDA hypofunction: In vitro safety assessment and plasma stability. Steroids. 2019 Jul:147:4-9. DOI:10.1016/j.steroids.2018.09.012