Description
Fmoc-N-Me-Lys(Boc)-OH is a peptide that mimics the structure of the natural substrate of serine protease. It has been shown to be stable in extracellular fluids and resistant to proteolytic degradation. The systematic sequence was designed to maximize the chance of binding to the active site of serine proteases while minimizing binding to other proteases. The maximal modifications were made on the amino acid side chains, which are most likely to interact with other proteins or with cell surfaces.
Chemical Properties
white to slight yellow to beige
Uses
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-N2-methyl-L-lysine is a lysine derivative[1].
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:
10.1080/10408398.2012.708368
