Description
Vitamin K2 is a naturally occurring vitamin that contains the basic structure of menadione and has anti-bleeding effects. It is a yellow crystal or oily liquid at room temperature, insoluble in water, soluble in organic solvents and vegetable oils, heat-resistant, but easily affected by light damage.
Effect
Vitamin K2 can promote the synthesis of prothrombin in the liver and regulate the synthesis of coagulation factors VII, IX and X, thereby accelerating blood coagulation. In addition, it plays an important role in the phosphorylation of glucose in cells. In some bacteria (such as mycobacteria), it can be used as a component of the respiratory chain.
Physiological function
The main physiological function of vitamin K2 is to promote the production of prothrombin (coagulation factor II) in the liver, and it also regulates the formation of coagulation factors VII, IX and X. Vitamin K deficiency, blood clotting time is prolonged, bleeding can occur in severe cases.
Uses
Vitamin K2 is a natural vitamin that is produced by gut bacteria. It is suitable for hemostasis: obstructive jaundice, biliary fistula, chronic diarrhea, hemorrhage in neonates, premature infants, and secondary vitamin K deficiency caused by long-term use of broad-spectrum antibiotics, sulfonamides, and excessive use of coumarins, salicids Bleeding from acid.
Definition
ChEBI: Menaquinone-4 is a menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. It has a role as a bone density conservation agent, a human metabolite, an antioxidant, an anti-inflammatory agent and a neuroprotective agent.
