Chemical Properties
clear yellow liquid after melting
Uses
1-Acetylindole may be used in the stereocontrolled synthesis of (±)-geissoschizine. It may be used in the preparation of (1-acetyl-κ
O-indolyl-κ
C2)tetracarbonylmanganese, via a standard cyclomanganation procedure.
Definition
ChEBI: N-Acetylindole is a member of indoles.
General Description
Quantum chemical calculations of ground state energy, geometrical structure and vibrational wavenumbers of 1-acetylindole has been carried out using density functional (DFT/B3LYP) method. Regioselective acylations of 1-acetylindole (
N-acetylindole) under Friedel-Crafts reaction has been reported. Reaction of 1-acetylindole with manganese(III) acetate in the presence of malonic acid, is reported to afford 4-acetyl-3,3
a,4,8
b-tetrahydro-2
H-furo[3,2-
b]indol-2-one.
