Chemical Properties
White powder
Uses
1-Adamantyl isocyanate may be used in the preparation of:
- adamantyl-functionalized nanoparticles, via thiol-isocyanate reaction of thiol-modified nanoparticles1 4-[3-(aryl or -cycloalkyl)ureido]butyryl compound
- 4-(3-adamantan-1-yl-ureido)butyric acid, via reaction with 4-aminobutanoic acid in DMF
- 4-(3-adamantan-1-yl-ureido)butyryloxy compound
- 12-(3-adamantan-1-yl-ureido) dodecanoic acid (AUDA)
- adamantyl-phenylsulfonamide ureas
- 1-adamantan-1-yl-3-(hydroxyalkyl)ureas, via reaction with with hydroxyalkylamines
Synthesis Reference(s)
The Journal of Organic Chemistry, 55, p. 4282, 1990
DOI: 10.1021/jo00301a014
General Description
1-Adamantyl isocyanate is an isocyanate derivative.
Purification Methods
Recrystallise the isocyanate from n-hexane and sublime it. Irritant. [Stetter & Wulff Chem Ber 95 2302 1962.]