Uses
Sphinganine-C20-1-phosphate is lethal to saccharomyces cerevisiae cells when accumulated thus may be used to regulate yeast cell growth.
General Description
Sphinganine-1-Phosphate is a phosphorylated derivative of C20 base sphinganine.
Biochem/physiol Actions
Exogenous sphinganine-1-phosphate activates sphingosine-1-phosphate receptor 1 (S1P1). It exhibits protective effects against hepatic and renal ischemia and reperfusion (IR). Sphingosine-1 phosphate and sphinganine-1-phosphate are bioactive lipid mediators. Sphinganine-1-phosphate acts opposite to sphingosine-1 phosphate activities. Increased concentration of sphinganine-1-phosphate acts as a potential biomarker for fumonisin exposure and toxicity in mice.
