Uses
Dibenzo[a,e]pyrene is a polyaromatic hydrocarbon with inherent carcinogenic properties.
Definition
ChEBI: Dibenzo[a,e]pyrene is an ortho- and peri-fused polycyclic arene.
General Description
Yellow crystals. Water insoluble.
Air & Water Reactions
Dust/air mixtures may ignite and explode. Insoluble in water.
Reactivity Profile
Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as DIBENZO(A,E)PYRENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.
Safety Profile
Confirmed carcinogen
with experimental neoplastigenic and
tumorigenic data. When heated to
decomposition it emits acrid smoke and
irritating fumes.
Carcinogenicity
Dibenzo[a,e]pyrene was assessed
in two initiation–promotion studies on mouse skin. One
of the studies gave positive results while other gave
negative results. Dibenzo[a,e]pyrene gave negative results
when tested for carcinogenicity by intramamillary administration
to rats.
