Uses
Saclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons
Uses
Saclofen has been used as a GABA
B receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.
Definition
ChEBI: 3-amino-2-(4-chlorophenyl)-1-propanesulfonic acid is an organochlorine compound.
Biological Activity
Selective antagonist at GABA B receptors.
Biochem/physiol Actions
Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.