Z-DQMD-FMK

Uses

Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK is an inhibitor for caspase-3, and inhibits Dihydroartemisinin (HY-N0176) and Dictamnine (HY-N0849) co-induced apoptosis[1].

Biological Activity

Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro .

References

1. susan s. chou*, michael s. clegg, alterations in protein kinase c activity and processing during zinc-deficiency-induced cell death, biochem. j. (2004) 383, 63–71 2. j. h. banga, e. s. han. differential response of mg132 cytotoxicity against small cell lung cancer cells to changes in cellular gsh contents. biochemical pharmacology 68 (2004) 659–666. 3. t. shimohata, h. zhao, εpkc may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model. stroke. 2007;38:375-380