Synthesis
GENERAL PROCEDURE: Ammonium chloride (0.54 g, 10 mmol) and ethanol (3 mL) were added to a 25 mL round bottom flask, followed by morpholine (10 mmol). The reaction mixture was placed on a magnetic stirrer and heated to reflux for 2 hours. After completion of the reaction, the solvent was removed by rotary evaporator to give morpholine hydrochloride as a white solid in quantitative yield.
References
[1] Synthetic Communications, 2015, vol. 45, # 22, p. 2601 - 2607
[2] Main Group Metal Chemistry, 2016, vol. 39, # 5-6, p. 175 - 181
[3] Patent: WO2008/95943, 2008, A1. Location in patent: Page/Page column 50; 122-123
[4] Advanced Synthesis and Catalysis, 2010, vol. 352, # 7, p. 1135 - 1136
[5] Patent: US2010/204235, 2010, A1. Location in patent: Page/Page column 5; 27; 28
