Originator
Budotitane,ZYF Pharm Chemical
Manufacturing Process
11.4 g (0.05 mol) of titantetraethoxid were mixed with solution of 15.8 g
(0.097mol) of benzoylaceton in 200 ml n-hexan. Reaction mixture was mixed
for 2 h at heating in N2 atmosphere. The precipitate obtained was filtered,
then the product was washed with hexan also and filtered. So there was
obtained the diethoxybis-(1-phenyl-1,3-butandionato)-titan, melting point
110°C.
Therapeutic Function
Antineoplastic
Pharmaceutical Applications
Budotitane is an octahedral Ti(IV) complex that was developed as a potential anticancer agent around
the same time as the anticancer properties of Cp
2TiCl
2 were discovered.
