Originator
Rhinoptil,Promonta,W. Germany,1974
Definition
ChEBI: Cafaminol is an oxopurine.
Manufacturing Process
21 g 8-chlorocaffeine and 15 g beta-N-methylaminoethanol are heated to
140°-160°C for 30 minutes. Then the temperature is increased for 15-20
minutes to 165°-170°C. On cooling a colorless mass of crystals results. This is
boiled with 50-60 ml ethanol and crystallized. Colorless crystals result which are soluble in water up to about 6%; pH of the aqueous solution is 6.9. The
yield is 19 g while the MP is 162°-164°C.
Therapeutic Function
Nasal decongestant
