4-Aminophenylacetonitrile

Chemical Properties

yellow to brown crystalline powder, crystals

Uses

4-Aminobenzyl Cyanide can be used to prevent or treat influenza.

Synthesis Reference(s)

Synthetic Communications, 22, p. 3189, 1992 DOI: 10.1080/00397919208021132

Synthesis

P-Nitrophenylacetonitrile (10 g, 61.67 mmol) was dissolved in methanol (50 mL). Add 10 per cent Pd/C (1.0g), Replace the reaction system four times with H2, and Stir at room temperature overnight in an H2 environment (0.5 MPa).TLC analysis, the reaction was complete, and the reaction solution was filtered through celite. The filtrate was concentrated under reduced pressure to give 8.08g of 4-Aminophenylacetonitrile; the yield was 99.1 per cent.