EXENDIN-4 (3-39)

Uses

Exendin-4 (3-39) is a peptide. Exendin-4 (3-39) is a truncated form of Exendin-4 (HY-13443) that lacks the first two amino acids. Exendin-4 is a potent Glucagon-like peptide-1 receptor (GLP-1r) agonist. Exendin-4 (3-39) and Exendin-4 can be used for the research of diabetic and hypothalamic-pituitary-adrenal (HPA) axis[1][2].

in vivo

References

[1] David Parkes, et al. Pharmacokinetic actions of exendin-4 in the rat: Comparison with glucagon-like peptide-1. (2001), 53(4), 260–267.
[2] Affiliations, et al. GLP-1(7-36)-amide and Exendin-4 stimulate the HPA axis in rodents and humans. Endocrinology. 2010 Jun;151(6):2629-40. DOI:10.1210/en.2009-0915