Isoindoline-5-carbonitrile

Uses

Isoindoline-5-carboxynitrile is a nitrile compound that can be used as a pharmaceutical intermediate.

Synthesis

Isoindoline-5-carbonitrile is a nitrile compound, which can be prepared from 5-bromoisoindoline-1,3-dione by a four-step reaction to obtain isoindoline-5-carbonitrile. Isoindoline-5-carbonitrile can be used to prepare the RHO kinase inhibitor 2-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)isoindoline-5-carbonitrile.