Uses
Lorazepam-d4 is labelled Lorazepam (L469850) which is a high-potency, intermediate-duration, 3-hydroxy benzodiazepine drug, It is often used to treat anxiety disorders.
References
[1] L G MILLER. Chronic benzodiazepine administration. I. Tolerance is associated with benzodiazepine receptor downregulation and decreased gamma-aminobutyric acidA receptor function.[J]. Journal of Pharmacology and Experimental Therapeutics, 1988, 246 1: 170-176.
[2] DAVID BALDWIN. Efficacy of drug treatments for generalised anxiety disorder: systematic review and meta-analysis.[J]. BMJ : British Medical Journal, 2011: d1199. DOI:
10.1136/bmj.d1199[3] BJOERN MOOSMANN Volker A Philippe Bisel. Characterization of the designer benzodiazepine diclazepam and preliminary data on its metabolism and pharmacokinetics[J]. Drug Testing and Analysis, 2014, 6 7-8: 757-763. DOI:
10.1002/dta.1628
