Description
Butabarbital (CRM) (Item No. 20088) is a certified reference material categorized as a barbiturate. It has a high abuse potential and increases risk of overdose morbidity and mortality in recreational drug users. Butabarbital is regulated as a Schedule III compound in the United States. Butabarbital (CRM) (Item No. 20088) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
Uses
Controlled substance (depressant). Sedative, hypnotic.
Uses
Butabarbital is also used as a soporific drug in various forms of insomnia and as a sedative. The most frequently used synonym is butizone.
Definition
ChEBI: Butabarbital is a member of barbiturates.
brand name
Butabarb (Alpharma);
Butalan (Lannett); Buticaps (Medpointe); Butisol Sodium
(Medpointe); Sarisol (Halsey).
Synthesis
Butabarbital, 5-ethyl-5-isobutylbarbituric acid (4.1.11), is also synthesized
in an analogous manner by condensation of |á-ethyl-|á-isobutylmalonic ester with urea [9].
References
[1] DRIPPS R D. Selective utilization of barbiturates as illustrated by a study of butabarbital sodium.[J]. Journal of the American Medical Association, 1948, 139 3: 148-150.
[2] LAURIE A ZAWERTAILO. Comparative abuse liability and pharmacological effects of meprobamate, triazolam, and butabarbital.[J]. Journal of Clinical Psychopharmacology, 2003, 23 3: 269-280. DOI:
10.1097/01.jcp.0000084031.22282.24
