Uses
Treatment of hyperphosphatae mia in patients with end stage renal disease.
brand name
Fosrenol
(Shire).
Flammability and Explosibility
Not classified
Mechanism of action
Lanthanum Carbonate inhibits phosphate absorption from the intestine and lowers the phosphate levels in the blood. Lanthanum Carbonate inhibits phosphate absorption from the intestine and lowers the phosphate levels in the blood.
Side effects
Nausea, Vomiting, Abdominal pain
in vitro
Lanthanum carbonate is an ideal phosphate binder. It prevents the adsorption of dietary phosphate by forming insoluble lanthanum phosphate. It has been reported that lanthanum carbonate binds phosphate optimally at pH 3–5, while retaining binding activity at pH 1–7. In vitro, studies suggest that the efficacy of lanthanum phosphate is comparable to that of aluminium compounds in binding with phosphate. The FDA has approved using lanthanum carbonate as a phosphate binder for renal failure patients.
