15-Epi prostaglandin A1

Description

15-epi PGA₁ is the 15(R) stereoisomer of PGA₁. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA₁ causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients. There are no published reports on the biological activity of 15-epi PGA₁ at this time.

Uses

15-epi PGA1 is the 15(R) stereoisomer of PGA1. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients. There are no published reports on the biological activity of 15-epi PGA1 at this time.

Uses

15-epi Prostaglandin A1 is a naturally occurring prostaglandin used in hypertension studies.

Definition

ChEBI: 15-epi-PGA1 is a prostanoid.

References

[1] L R KRAKOFF. Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin.[J]. Clinical science and molecular medicine. Supplement, 1975, 2: 311s-313s. DOI: 10.1042/cs048311s