Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)-

Description

Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor extracted from patent WO2009123623A1, has a Ki of <20 nM.

Cathepsin Inhibitor 2 (Please refer to paragraph 0229 for detailed information) potently inhibits Cathepsin S, Cathepsin F, Cathepsin L, and Cathepsin B with Kis of <20 nM, 21-500 nM, 21-500 nM, and 21-500 nM, respectively[1].

References

[1]. LINK, John, O, et al. DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS. WO2009123623A1.