ARM1
- Product NameARM1
- CAS68729-05-5
- CBNumberCB03152553
- MFC16H14N2S
- MW266.36
- MDL NumberMFCD01816130
- MOL File68729-05-5.mol
Chemical Properties
storage temp. | Store at -20°C |
solubility | ≤1mg/ml in ethanol;10mg/ml in DMSO;15mg/ml in dimethyl formamide |
form | crystalline solid |
color | Off-white to light yellow |
ARM1 Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Cayman Chemical 15865 | 5mg | $62 | ARM1 ≥95% |
Buy |
Cayman Chemical 15865 | 10mg | $115 | ARM1 ≥95% |
Buy |
Cayman Chemical 15865 | 50mg | $477 | ARM1 ≥95% |
Buy |
Cayman Chemical 15865 | 100mg | $834 | ARM1 ≥95% |
Buy |
Matrix Scientific 135662 | 2.500g | $1266 | 4-(4-Benzylphenyl)-1,3-thiazol-2-amine 95%+ |
Buy |
ARM1 Chemical Properties,Usage,Production
Description
Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 from LTA4 and cleaves the chemotactic peptide Pro-Uses
Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 μM) and conversion of LTA4 to LTB4 by purified LTA4 hydrolase (Ki = 2.3 μM). ARM1 does not significantly affect the hydrolysis of Pro-Gly-Pro by LTA4 hydrolase.[Cayman Chemical]References
[1]. stsiapanava a, olsson u, wan m, et al. binding of pro-gly-pro at the active site of leukotriene a4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. proc natl acad sci u s a. 2014 mar 18;111(11):4227-32.[2]. haeggstrm jz. leukotriene a4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene b4 biosynthesis. j biol chem. 2004 dec 3;279(49):50639-42.
[3]. snelgrove rj, jackson pl, hardison mt, et al. a critical role for lta4h in limiting chronic pulmonary neutrophilic inflammation. science. 2010 oct 1;330(6000):90-4.
Preparation Products And Raw materials
ARM1 Supplier
Global(31)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
+1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 | |
+1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 | |
021-QQ:65489617 15618227136 |
Sales@ATKchemical.com | China | 7296 | 58 | |
021-58447131 13564518121 |
sales@dcchemicals.com | China | 9409 | 58 | |
021-20432219 13918097649 |
li_jinfei@acblock-lab.com | China | 9593 | 58 | |
18818260767 | sales@chemegen.com | China | 11218 | 58 | |
13621943973; 13621943973 |
sales@jamxmpharmatech.com | China | 1111 | 58 | |
15092083467 | 18660263263@163.com | China | 2425 | 58 | |
400-8210725 4008210725 |
malulu@leyan.com | China | 39995 | 58 | |
4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
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