Chemical Properties
Off-White Solid
Uses
6-Hydroxychlorzoxazone has been used for HPLC-based metabolic assays of chlorzoxazone.
Uses
A major metabolite of chlorzoxazone. Formed by the actions of cytochrome P450IIE1
Definition
ChEBI: 6-Hydroxychlorzoxazone is a benzoxazole.
Biochem/physiol Actions
6-hydroxy Chlorzoxazone is a novel metabolite of chlorzoxazone. It is formed by the hydroxylation of chlorzoxazone by cytochrome P450 family 2 subfamily E member 1 (CYP2E1) enzyme. The determination of formation and clearance of 6-hydroxychlorzoxazone is used as a reliable marker of CYP2E1 metabolic activity.
