Description
3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen which has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT
2 serotonin receptors (pEC
50 = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT
2A and 5-HT
2C, respectively). This product is intended for research and forensic applications.
Uses
3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen that has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50s = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT2A and 5-HT2C, respectively). This product is intended for research and forensic applications.[Cayman Chemical]
References
[1] ARIANE WOHLFARTH Sebastian D Wolfgang Weinmann. LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum[J]. Analytical and Bioanalytical Chemistry, 2010, 396 7: 2403-2414. DOI:
10.1007/s00216-009-3394-4[2] PABLO R MOYA. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors.[J]. Journal of Pharmacology and Experimental Therapeutics, 2007, 321 3: 1054-1061. DOI:
10.1124/jpet.106.117507[3] FUMIKO NAGAI Kanako S H K Ryouichi Nonaka. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain[J]. European journal of pharmacology, 2007, 559 2: Pages 132-137. DOI:
10.1016/j.ejphar.2006.11.075
