Chemical Properties
white to light yellow crystal powder
Uses
L-Azetidine-2-carboxylic acid has been used as a:
- collagen synthesis inhibitor
- protein folding antagonist
- as a standard in liquid chromatography-mass spectrometry
Uses
Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides.
Uses
(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.
Definition
ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid.
General Description
L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.
Biochem/physiol Actions
Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.
Safety Profile
Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx.
