Keliximab Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0628924 | 1mg | $325 | Keliximab 98.23% |
Buy |
| ChemScene CS-0628924 | 5mg | $812 | Keliximab 98.23% |
Buy |
| ChemScene CS-0628924 | 10mg | $1300 | Keliximab 98.23% |
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| aablocks AA00AM3S | 1mg | $572 | Keliximab ≥95%(SDS-PAGE&SEC-HPLC) |
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| aablocks AA00AM3S | 5mg | $1426 | Keliximab ≥95%(SDS-PAGE&SEC-HPLC) |
Buy |
Keliximab Chemical Properties,Usage,Production
Uses
Keliximab (SB-210396) is a chimeric human/macaque IgG1 anti-CD4 monoclonal antibody with a Ki value of 1.0 nM for soluble CD4. Keliximab blocks T cell proliferation and inhibits IL-2 production. Keliximab can be used for cancer research[1][2].in vivo
Keliximab (5-125 mg/kg; i.v., once) decreases CD4+ T cells[1].
| Animal Model: | Transgenic mice bearing human CD4 molecules on their T cells[1] |
| Dosage: | 5-125 mg/kg |
| Administration: | Intravenous injection, 5-125 mg/kg, once |
| Result: | Dose-dependently down-modulated CD4 and rapidly declined the number of circulating CD4+ T cells compared with clenoliximab. |
References
[1] Sharma A, et al. Comparative pharmacodynamics of keliximab and clenoliximab in transgenic mice bearing human CD4. J Pharmacol Exp Ther. 2000 Apr;293(1):33-41. PMID:10734150[2] Anderson D, et al. A primatized MAb to human CD4 causes receptor modulation, without marked reduction in CD4+ T cells in chimpanzees: in vitro and in vivo characterization of a MAb (IDEC-CE9.1) to human CD4. Clin Immunol Immunopathol. 1997 Jul;84(1):73-84. DOI:10.1006/clin.1997.4363
Preparation Products And Raw materials
Keliximab Suppliers
Global(18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 027-65279366 18108604356 |
products@biolabreagent.com | China | 9864 | 58 | |
| 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 9920 | 65 | |
| 15026964105 | 2881489226@qq.com | China | 87240 | 60 | |
| 177-54423994 17754423994 |
2853530910@QQ.com | China | 7996 | 62 | |
| 027-65317797 15926423062 |
422450190@qq.com | China | 10302 | 58 | |
| 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 | |
| 13720134139 086-15871494362 13720134139 |
orders@jknbiochem.com | China | 7284 | 58 | |
| 021-65675885 18964387627 |
customer_service@efebio.com | China | 11963 | 58 | |
| 15111215862 18229892877 |
3062105966@qq.com | China | 5571 | 58 | |
| 027-87008169 17762441161 |
info@atagenix.com | China | 9997 | 58 |
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