Norfenefrinhydrochlorid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

DL-NORPHENYLEPHRINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R22:Gesundheitsschädlich beim Verschlucken.

• Chemische Eigenschaften

  white to almost white crystalline powder

• Originator

  Zordel,Grelan,Japan,1970

• Verwenden

  rac Norphenylephrine Hydrochloride is an Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists.

• Definition

  ChEBI: Norfenefrine hydrochloride is a member of phenols.

• Manufacturing Process

  100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

• Therapeutic Function

  Adrenergic

DL-NORPHENYLEPHRINE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Norfenefrinhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(98)Suppliers

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