N-Prop-2-inylphthalimid

Bezeichnung:N-Prop-2-inylphthalimid

CAS-Nr7223-50-9

Englisch Name:N-PROPARGYLPHTHALIMIDE

CBNumberCB8755180

SummenformelC11H7NO2

Molgewicht185.18

MOL-Datei7223-50-9.mol

Synonyma

N-Prop-2-inylphthalimid

N-Prop-2-inylphthalimid physikalisch-chemischer Eigenschaften

Schmelzpunkt	148-152 °C
Siedepunkt	304.1±25.0 °C(Predicted)
Dichte	1.318±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
Aggregatzustand	powder to crystal
pka	-2.54±0.20(Predicted)
Farbe	White to Light yellow to Light orange
InChI	1S/C11H7NO2/c1-2-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h1,3-6H,7H2
InChIKey	PAZCLCHJOWLTGA-UHFFFAOYSA-N
SMILES	O=C1N(CC#C)C(=O)c2ccccc12

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/37/38-36-22
S-Sätze:	37/39-26
WGK Germany	3
HazardClass	IRRITANT
HS Code	29251995
Speicherklasse	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Eye Irrit. 2

Gefahreninformationscode (GHS)

N-PROPARGYLPHTHALIMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36:Reizt die Augen.
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Beige to orange powder
Synthese

1074-82-4

106-96-7

7223-50-9

General procedure for the synthesis of N-propargyl phthalimide from phthalimide potassium salt and 3-bromopropargyl: 8.4 mmol of 3-bromopropargyl and 8.4 mmol of phthalimide potassium salt were dissolved in 10 mL of N,N-dimethylformamide. Subsequently, 0.2 g of manganese dioxide solid was added as a catalyst. The reaction mixture was stirred at 28°C for 2 hours. Upon completion of the reaction, the mixture was diluted by adding 100 mL of ethyl acetate to the mixture, followed by washing with water to collect the organic layer. The organic layer was further washed with saturated aqueous sodium chloride solution and dried with anhydrous sodium sulfate. The dried organic phase was separated and purified by column chromatography with the eluent being a solvent mixture of petroleum ether and ethyl acetate (5:1, v/v) to obtain pure N-propargyl phthalimide.
Einzelnachweise
[1] Patent: CN105669525, 2016, A. Location in patent: Paragraph 0062; 0063; 0082
[2] Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2002, vol. 377, p. 13 - 18
[3] Phosphorus, Sulfur and Silicon and the Related Elements, 2004, vol. 179, # 8, p. 1611 - 1614
[4] Patent: WO2005/82892, 2005, A2. Location in patent: Page/Page column 58-59
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 27, p. 3941 - 3946

N-PROPARGYLPHTHALIMIDE Upstream-Materialien And Downstream Produkte

N-Prop-2-inylphthalimid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

7223-50-9, N-PROPARGYLPHTHALIMIDE Verwandte Suche:

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