Cyclophosphamid
Bezeichnung:Cyclophosphamid
CAS-Nr50-18-0
Englisch Name:Cyclophosphamide
CBNumberCB8547532
SummenformelC7H15Cl2N2O2P
Molgewicht261.09
MOL-Datei50-18-0.mol
Synonyma
Cyclophosphamid
N,N-Bis(2-chlorethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amin-2-oxid
Cyclophosphamid physikalisch-chemischer Eigenschaften
Schmelzpunkt | 41-45°C |
Siedepunkt | 336.1±52.0 °C(Predicted) |
Dichte | 1.33±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
Löslichkeit | ≥11.85 mg/mL in H2O with gentle warming and ultrasonic; ≥13.05 mg/mL in DMSO; ≥50.8 mg/mL in EtOH |
pka | 2.84±0.20(Predicted) |
Aggregatzustand | solid |
Farbe | White to off-white |
Wasserlöslichkeit | Soluble. 1-5 g/100 mL at 23 ºC |
BCS Class | 1,3 |
Stabilität | Stable, but light sensitive. Incompatible with oxidizing agents. |
CAS Datenbank | 50-18-0(CAS DataBase Reference) |
IARC | 1 (Vol. 26, Sup 7, 100A) 2012 |
NIST chemische Informationen | 2-[Bis(2-chloroethylamino)]-tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide(50-18-0) |
EPA chemische Informationen | Cyclophosphamide (50-18-0) |
S-Sätze: | 22-24/25 |
RIDADR | UN 1851 |
HazardClass | 6.1(b) |
PackingGroup | III |
Giftige Stoffe Daten | 50-18-0(Hazardous Substances Data) |
Toxizität | LD50 oral in rat: 100mg/kg |