Natriumpalmitat

Bezeichnung:Natriumpalmitat

CAS-Nr408-35-5

Englisch Name:Sodium Palmitate

CBNumberCB8432520

SummenformelC16H31NaO2

Molgewicht278.41

MOL-Datei408-35-5.mol

Synonyma

Natriumpalmitat

Natriumpalmitat physikalisch-chemischer Eigenschaften

Schmelzpunkt	283-290 °C (lit.)
storage temp.	2-8°C
Löslichkeit	very faint turbidity in hot EtOH50vol%
Aggregatzustand	Powder
Farbe	White
BRN	3575882
LogP	7.154 (est)
CAS Datenbank	408-35-5(CAS DataBase Reference)
EPA chemische Informationen	Hexadecanoic acid, sodium salt (408-35-5)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36
S-Sätze:	22-24/25-26
WGK Germany	1
RTECS-Nr.	RT4945000
HS Code	29157000
Giftige Stoffe Daten	408-35-5(Hazardous Substances Data)

Gefahreninformationscode (GHS)

Sodium Palmitate Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white powder
Chemische Eigenschaften
Sodium palmitate, white solid, soluble, froth or foam upon shaking the H2O solution (soap), formed by reaction of NaOH and palmitic acid (in alcoholic solution) and evaporating. Used as a source of palmitate.
Verwenden
Polymerization catalyst for synthetic rubbers, laundry and toilet soaps, detergents, cosmetics, pharmaceuticals, printing inks, and as an emulsi- fier.
Verwenden
Sodium Palmitate is the sodium salt of palmitic acid. It functions as a binder, emulsifier, and anticaking agent.
Verwenden
Sodium palmitate (PA) has been used:
- to induce inflammation and thrombosis pathway in murine macrophage cell line RAW 264.7 cell line by activating reactive oxygen species (ROS) production, Janus-kinase (JNK) signalling and release of histone H3 by western blotting and cell viability by MTT assay
- to induce lipogenesis in AML12 cells and primary hepatocytes to analyse the effect of irisin on PA induced lipogenesis and related signal pathways by western blot analysis and quantitative PCR analysis
- as a component in free fatty acid mixture to induce cellular steatosis in HepG2 cell lines and determination of lipid accumulation by Oil-Red-O staining
Hazard
A poison. Combustible.
Biochem/physiol Actions
Sodium palmitate is the sodium salt of palmitic acid, a component in hard soaps. Palmitic acid is a common saturated fatty acid and produced during fatty acid synthesis. Sodium palmitate enhances lipogenesis, cellular steatosis in various cell lines. Palmitate induces cell death in human epidermal growth factor receptor 2 (HER2)/neu-positive cells and breast cancer cell lines like MCF-7 due to enhanced fatty acid accumulation. Sodium palmitate induces lipoapoptosis in L02 and HepG2 liver cells by inducing glycogen synthase kinase-3β (GSK3β) expression.
Sicherheitsprofil
A poison by intravenous route. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
läuterung methode
It crystallises from EtOH and is dried in an oven. [Beilstein 2 IV 1157.]

Sodium Palmitate Upstream-Materialien And Downstream Produkte

Natriumpalmitat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

408-35-5, Sodium Palmitate Verwandte Suche:

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