9,10-DIDEHYDRO-6-METHYL-ERGOLINE-8-CARBOXYLIC ACID Struktur

Lysergsure

Bezeichnung:Lysergsure

CAS-Nr82-58-6

Englisch Name:9,10-DIDEHYDRO-6-METHYL-ERGOLINE-8-CARBOXYLIC ACID

CBNumberCB8261074

SummenformelC16H16N2O2

Molgewicht268.31

MOL-Datei82-58-6.mol

Synonyma

Lysergsure

Lysergsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	>170°C (dec.)
alpha	D20 +40° (c = 0.5 in pyridine)
Siedepunkt	411.48°C (rough estimate)
Dichte	1.1028 (rough estimate)
Dampfdruck	0Pa at 20℃
Brechungsindex	1.6240 (estimate)
storage temp.	Controlled Substance, -20°C Freezer
pka	3.44, 7.68(at 25℃)
Wasserlöslichkeit	267mg/L at 20℃
LogP	-0.7 at 20℃

Sicherheit

HS Code	29396300
DEA Controlled Substances	CSCN: 7300 CSA SCH: Schedule III NARC: No

Gefahreninformationscode (GHS)

9,10-DIDEHYDRO-6-METHYL-ERGOLINE-8-CARBOXYLIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
A precursor of the semisynthetic ergot derivatives, but having no biological activity itself. It is subject to controls under the Controlled Substances Act of 1970 in the United States, since it is the immediate precursor for the synthesis of LSD. Lysergic acid is obtained by hydrolysis of ergot alkaloids, either obtained from grains infected with Claviceps or, more commonly, by fermentation in submerged culture.
Chemische Eigenschaften
beige to brown powder
Verwenden
Labelled Lysergic acid. Lysergic acid and iso-lysergic acid are the main cleavage products formed on alkaline hydrolysis of the alkaloids which are characteristic of ergot. Potent hallucinogen; non-selective serotonin receptor agonist. Controlled substanc
Verwenden
Lysergic acid and iso-lysergic acid are the main cleavage products formed on alkaline hydrolysis of the alkaloids which are characteristic of ergot. Potent hallucinogen; non-selective serotonin receptor agonist. Controlled substance.
Definition
ChEBI: An ergoline alkaloid comprising 6-methylergoline having additional unsaturation at the 9,10-position and a carboxy group at the 8-position.
Synthesis Reference(s)
Journal of the American Chemical Society, 78, p. 3087, 1956 DOI: 10.1021/ja01594a039
Flammability and Explosibility
Not classified
läuterung methode
It crystallises from water as a hydrate. The methyl ester crystallises from C6H6 and has m 168o; the amide [478-94-4] has m 242o(dec) (from MeOH) and []546 +15o (c 0.5, pyridine).The (-)-hydrochloride has m 208-210o(dec, from MeOH). [Kornfeld et al. J Am Chem Soc 7 6 5256 1954,Kornfeld et al. J Am Chem Soc 78 3087 1956, Beilstein 25 III/IV 934,]

9,10-DIDEHYDRO-6-METHYL-ERGOLINE-8-CARBOXYLIC ACID Upstream-Materialien And Downstream Produkte

82-58-6, 9,10-DIDEHYDRO-6-METHYL-ERGOLINE-8-CARBOXYLIC ACID Verwandte Suche:

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