5-METHOXY-2-METHYLINDOLE Struktur

5-Methoxy-2-methylindol

Bezeichnung:5-Methoxy-2-methylindol

CAS-Nr1076-74-0

Englisch Name:5-METHOXY-2-METHYLINDOLE

CBNumberCB8174569

SummenformelC10H11NO

Molgewicht161.2

MOL-Datei1076-74-0.mol

Synonyma

5-Methoxy-2-methylindol

5-Methoxy-2-methylindol physikalisch-chemischer Eigenschaften

Schmelzpunkt	86-88 °C (lit.)
Siedepunkt	145 °C / 1.5mmHg
Dichte	1.0840 (rough estimate)
Brechungsindex	1.5200 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Soluble in methanol (very faint turbidity.)
pka	17.28±0.30(Predicted)
Aggregatzustand	Crystalline Powder or Crystals
Farbe	White to light beige
InChIKey	VSWGLJOQFUMFOQ-UHFFFAOYSA-N
CAS Datenbank	1076-74-0(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	37/39-26
WGK Germany	3
HazardClass	IRRITANT
HS Code	29339900

Gefahreninformationscode (GHS)

5-METHOXY-2-METHYLINDOLE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
5-methoxy-2-methylindole is a useful organic raw material. It can be used as the reactant in the preparation of indolylquinoxalines by condensation reactions, in preparation of alkylindoles via Ir-catalyzed reductive alkylation, in arylation reactions in the presence of a palladium acetate catalyst, in enantioselective Friedel-Crafts alkylation, as well as in stereo selective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. It is also employed in inhibiting the chlorinating activity of myeloperoxidase (MPO) and in the metabolic synthesis of acrylacetic acid anti-inflammatory synthesis.
Chemische Eigenschaften
white to light beige crystalline powder or
Verwenden
It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.
Verwenden
reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5
Verwenden
An indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid antiinflammatory synthesis.
Definition
ChEBI: 5-Methoxy-2-methyl-1H-indole is a member of indoles.
Einzelnachweise
https://www.alfa.com/en/catalog/B21348/
http://www.sigmaaldrich.com/catalog/product/aldrich/m15451?lang=en&region=US
https://pubchem.ncbi.nlm.nih.gov/compound/5-Methoxy-2-methylindole#section=2D-Structure

5-METHOXY-2-METHYLINDOLE Upstream-Materialien And Downstream Produkte

5-Methoxy-2-methylindol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1076-74-0, 5-METHOXY-2-METHYLINDOLE Verwandte Suche:

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