PYRILAMINE Struktur

Mepyramin

Bezeichnung:Mepyramin

CAS-Nr91-84-9

Englisch Name:PYRILAMINE

CBNumberCB7775947

SummenformelC17H23N3O

Molgewicht285.38

MOL-Datei91-84-9.mol

Synonyma

Mepyramin

Mepyramin physikalisch-chemischer Eigenschaften

Schmelzpunkt	131-132 °C
Siedepunkt	bp5 201°; bp0.06 168-172°
Dichte	1.0141 (rough estimate)
Brechungsindex	nD25 1.5760-1.5765
pka	pKa 4.02(H2O t=25 c=0.002 to 0.01) (Uncertain);8.92 (Uncertain)
Wasserlöslichkeit	3.425g/L(37.5 ºC)
EPA chemische Informationen	Mepyramine (91-84-9)

Sicherheit

Giftige Stoffe Daten	91-84-9(Hazardous Substances Data)
Toxizität	LD50 orally in mice: 312 mg/kg (Schlichtergroll)

Gefahreninformationscode (GHS)

PYRILAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden
Antihistaminic.
Verwenden
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine also known as pyrilamine works in synergism with diclofenac as a therapeutic alternative for clinical management of inflammatory pain.
Verwenden
Pyrilamine is also used for allergy symptoms and rhinitis.
Definition
ChEBI: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Trademarks
Histavet-P [Veterinary] (Schering-Plough Animal Health); Pymafed (HoechstRoussel).
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1999, 1946 DOI: 10.1021/ja01214a037
Allgemeine Beschreibung
Viscous brown liquid.
Air & Water Reaktionen
May be sensitive to light. Insoluble in water.
Reaktivität anzeigen
PYRILAMINE neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides.
Health Hazard
SYMPTOMS: Exposure to PYRILAMINE may cause somnolence, central nervous system depression and gastrointestinal disturbances. It may also cause drowsiness, dryness of the mouth, headache, nausea, tachycardia, urinary retention, nervousness, disorientation, staggering gait, hallucinations, stupor, coma, hyperflexia, tremors, excitement, nystagmus, hyperthermia, convulsions, agranulocytosis and aplastic anemia.
Brandgefahr
Flash point data for PYRILAMINE are not available; however, PYRILAMINE is probably combustible.

Mepyramin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

91-84-9, PYRILAMINE Verwandte Suche:

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