1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine Struktur

(R)-1-[[[(2-Aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethan-1,2-diyldihexadecanoat

Bezeichnung:(R)-1-[[[(2-Aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethan-1,2-diyldihexadecanoat

CAS-Nr923-61-5

Englisch Name:1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine

CBNumberCB7742028

SummenformelC37H74NO8P

Molgewicht691.97

MOL-Datei923-61-5.mol

Synonyma

(R)-1-[[[(2-Aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethan-1,2-diyldihexadecanoat

(R)-1-[[[(2-Aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethan-1,2-diyldihexadecanoat physikalisch-chemischer Eigenschaften

Schmelzpunkt	195.0 to 199.0 °C
Siedepunkt	723.6±70.0 °C(Predicted)
Dichte	1.010±0.06 g/cm3(Predicted)
storage temp.	-20°C
Löslichkeit	Methanol (Slightly)
Aggregatzustand	Solid
pka	1.17±0.50(Predicted)
Farbe	White to Off-White
BRN	1730601
InChIKey	SLKDGVPOSSLUAI-BSICABFTNA-N
SMILES	[C@H](COP(O)(=O)OCCN)(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC \|&1:0,r\|

Sicherheit

WGK Germany	3
HS Code	29232000

Gefahreninformationscode (GHS)

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally occurring PE containing C16:0 fatty acids at the sn-1 and sn-2 positions. It belongs to a class of phospholipids that are the most abundant lipids in the inner leaflet of the plasma membrane. 1,2-DPPE interacts with cholesterol to form a condensed lipid monolayer with tight hydrogen bonding of the 1,2-DPPE interheadgroups, resulting in a more fluid membrane that may aid in transport and signaling across the bilayer.
1,2-Dipalmitoyl-sn-glycero-3-PE MaxSpec^® standard is a quantitative grade standard of 1,2-dipalmitoyl-sn-glycero-3-PE that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 1,2-dipalmitoyl-sn-glycero-3-PE MaxSpec^® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Verwenden
16:0 PE has been used:
- for the preparation of perfluorocarbon (PFC) nanoparticles
- for lipid binding by liposome flotation assays
- to characterize the metabolic fate of synaptamide in a dopaminergic cell line
Verwenden
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is used in model membrane .
Definition
ChEBI: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine is a 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the 1- and 2-acyl groups are both specified as hexadecanoyl (palmitoyl). It has a role as a mouse metabolite. It is functionally related to a hexadecanoic acid. It is a tautomer of a 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion.
Application
1,2-Dipalmitoyl-sn-glycero-3-phosphorylethanolamine used in the synthesis ultra-thin membranes to facilitate the transfer of islets of Langerhans in the attenuation of early graft loss in avoidance of immunosuppressive therapy. Also used in the synthesis of immunoliposomes containing TAT cells for tumor cell internalization and cytotoxicity.
Allgemeine Beschreibung
Phosphatidylethanolamine is an aminophospholipid. It is present in eukaryotic and prokaryotic cells. Phosphatidylethanolamine is one of the most abundant glycerophospholipids in biological membranes. It is found in nervous tissue.
Biochem/physiol Actions
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid, a lipid component in cell membrane .

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine Upstream-Materialien And Downstream Produkte

(R)-1-[[[(2-Aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethan-1,2-diyldihexadecanoat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

923-61-5, 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine Verwandte Suche:

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