D-Valin

Bezeichnung:D-Valin

CAS-Nr640-68-6

Englisch Name:D-Valine

CBNumberCB7291278

SummenformelC5H11NO2

Molgewicht117.15

MOL-Datei640-68-6.mol

Synonyma

D-Valin

D-Valin physikalisch-chemischer Eigenschaften

Schmelzpunkt	>295 °C (subl.)(lit.)
Siedepunkt	213.6±23.0 °C(Predicted)
alpha	-27.5 º (c=5, 5N HCl)
Dichte	1.2000 (estimate)
Brechungsindex	-27 ° (C=8, 6mol/L HCl)
storage temp.	room temp
Löslichkeit	56 g/L (20°C)
Aggregatzustand	Crystalline Powder
pka	2.37±0.10(Predicted)
Farbe	White to off-white
Optische Aktivität	[α]23/D 32.0 to 24.0°, c = 8 in 6 M HCl
Wasserlöslichkeit	56 g/L (20 ºC)
BRN	1721135
InChIKey	KZSNJWFQEVHDMF-SCSAIBSYSA-N
LogP	0.289 (est)
CAS Datenbank	640-68-6(CAS DataBase Reference)
NIST chemische Informationen	2-Amino-3-methylbutanoic acid(D)(640-68-6)
EPA chemische Informationen	D-Valine (640-68-6)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	22-24/25-36-26
WGK Germany	3
RTECS-Nr.	YV9360000
TSCA	Yes
HS Code	29224995

Gefahreninformationscode (GHS)

D-Valine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to off-white crystalline powder
Verwenden
D-Valine is an isomer of the essential amino acid L-Valine. D-Valine has been used as a selective agent in epithelial cells in culture since it inhibits cells that lack the enzyme D-amino acid oxidase . D-Valine has also been shown to inhibit proliferation of contaminating fibroblasts in smooth muscle cells from human myometrium. D-Valine solution showed tumor growth inhibition and improvements of the nutritional status in AH109A hepatoma-bearing rats.
Verwenden
D-Valine is an isomer of the essential amino acid L-Valine. D-Valine has been used as a selective agent in epithelial cells in culture since it inhibits cells that lack the enzyme D-amino acid oxidase. D-Valine has also been shown to inhibit proliferation of contaminating fibroblasts in smooth muscle cells from human myometrium. D-Valine solution showed tumor growth inhibition and improvements of the nutritional status in AH109A hepatoma-bearing rats.
Definition
ChEBI: The D-enantiomer of valine.
Allgemeine Beschreibung
L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.
Biochem/physiol Actions
D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.

D-Valine Upstream-Materialien And Downstream Produkte

D-Valin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

640-68-6, D-Valine Verwandte Suche:

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