GD2-GANGLIOSIDE

GD2-GANGLIOSIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  lyophilized powder

• Verwenden

  Disialoganglioside-GD2 from bovine brain has been used:
  
  • in the ganglioside- enzyme-linked immunosorbent assay (ELISA)
  • in capture ELISA with anti-GD2 antibody (ch14.18)
  • as a control to test its effect on reactivating autophagy in primary fibroblasts
  
  

• Allgemeine Beschreibung

  Disialoganglioside GD2 is a cell surface-associated glycosphingolipid, which comprises sialic acid moiety and is regarded as a carbohydrate antigen.. It is expressed in the skin melanocytes, central and peripheral nervous system.

• Biochem/physiol Actions

  Disialoganglioside GD2 is expressed in neuroblastoma, melanoma and small cell lung cancer. It is an immunotherapeutic target and is also regarded as a tumor-associated antigen. GD2 may favor cell migrationin tumors by promoting cell growth, as well as extracellular matrix component attachment.

GD2-GANGLIOSIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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