Alcuroniumchlorid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H300：Lebensgefahr bei Verschlucken.

Alcuronium Chloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Alloferin, Roche ,UK ,1966

• Verwenden

  Alcuronium Dichloride exists as a neuromuscular blocking agent with ganglion blocking activity. Binds to muscarinic M2 receptors.

• Definition

  ChEBI: Alcuronium chloride is chloride salt of alcuronium. It contains an alcuronium.

• Manufacturing Process

  31 g of diallylnortoxiferine diiodide are suspended in 1 liter of water and shaken with 1,100 ml of Amberlite IRA-400 [chloride ion form, described Merck Index, 7th edition, Merck and Co., Inc., Rahway, New Jersey (1960), page 1584], for 2 hours. The diiodide thereby goes into solution. The ion exchanger is filtered off and then washed in 3 portions with a total of 1 liter of water. The combined filtrates are then allowed to run through a column of 300 ml of Amberlite IRA-400 (chloride ion form), rinsed with 300 ml of water and the eluate evaporated to dryness in a vacuum while excluding air. The residue gives on recrystallization from methanol/ethanol crystalline pure colorless diallylnortoxiferine dichloride in a yield of 18.6 g. The compound contains 5 mols of water of crystallization after equilibration in air.

• Trademarks

  Alloferin (Hoffmann-LaRoche-International).

• Therapeutic Function

  Muscle relaxant

15180-03-7, Alcuronium Chloride Verwandte Suche: