1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrencarbonsäure, (1R-(1 alpha, 4a beta, 10a alpha))-

Bezeichnung:1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrencarbonsäure, (1R-(1 alpha, 4a beta, 10a alpha))-

CAS-Nr1740-19-8

Englisch Name:Dehydroabietic acid

CBNumberCB6424042

SummenformelC20H28O2

Molgewicht300.44

MOL-Datei1740-19-8.mol

Synonyma

[1R-(1α,4aβ,10aα)]-1,2,3,4,4a,9,10,10a-Octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylsure

1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrencarbonsäure, (1R-(1 alpha, 4a beta, 10a alpha))-

1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrencarbonsäure, (1R-(1 alpha, 4a beta, 10a alpha))- physikalisch-chemischer Eigenschaften

Schmelzpunkt	174-176℃
Siedepunkt	394.13°C (rough estimate)
Dichte	1.058
Brechungsindex	1.5404 (estimate)
storage temp.	Sealed in dry,Store in freezer, under -20°C
Löslichkeit	DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 10 mg/ml
Aggregatzustand	A solid
pka	4.66±0.40(Predicted)
Farbe	White to yellow
InChIKey	NFWKVWVWBFBAOV-UHFFFAOYSA-N
LogP	6.120 (est)
EPA chemische Informationen	Dehydroabietic acid (1740-19-8)

Sicherheit

Kennzeichnung gefährlicher	T,N
R-Sätze:	25-50
S-Sätze:	45-61
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	1
HS Code	29161900

Gefahreninformationscode (GHS)

Dehydroabietic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
White Solid or Colorless needle crystal, Slightly soluble in water, soluble in methanol, ethanol, DMSO and other organic solvents. It is an abietane diterpenic resin acid that is obtained from Pinus resin.
Verwenden
Dehydroabietic Acid is a resin acid found commonly in rosin. Dehydroabietic Acid is used in rosin-type nucleating agent for polypropylene (PP). Dehydroabietic Acid is used commonly in the synthesis of surfactants, antioxidants and chiral catalysts.
Definition
ChEBI: Dehydroabietic acid is an abietane diterpenoid that is abieta-8,11,13-triene substituted at position 18 by a carboxy group. It has a role as a metabolite and an allergen. It is an abietane diterpenoid, a monocarboxylic acid and a carbotricyclic compound. It derives from an abietic acid. It is a conjugate acid of a dehydroabietate.
Application
Dehydroabietic acid (DHA or DAA) is a bioactive phytochemical, diterpenoid found in various Pinus species. It is a resin acid and a derivative of abietic acid (AA).
Dehydroabietic acid has been used as a reference standard:
to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)
to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy
to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis
Biochem/physiol Actions
Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrencarbonsäure, (1R-(1 alpha, 4a beta, 10a alpha))- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1740-19-8, Dehydroabietic acid Verwandte Suche:

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