4-(3-(5H-Dibenz(b,f)azepin-5-yl)propyl)-1-piperazinethanol

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H410：Sehr giftig für Wasserorganismen mit langfristiger Wirkung.

• Sicherheit

  P273：Freisetzung in die Umwelt vermeiden.

  P501：Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

OPIPRAMOL Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Crystalline Solid

• Originator

  Insidon,Geigy,W. Germany,1962

• Verwenden

  Antidepressant; antipsychotic

• Definition

  ChEBI: 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.

• Manufacturing Process

  A solution of 5-(3-toluene-p-sulfonyloxypropyl)dibenzazepine (9.2g) and 1-(2hydroxyethyl)piperazine (8.6g) in anhydrous toluene (50 cc) is heated at boiling point under reflux for 4 hours.
  After cooling, distilled water (75 cc) is added. The aqueous phase is decanted. The toluene solution is washed with distilled water (25 cc) and then extracted with N hydrohloric acid (40 cc). The hydrochloric acid solution is made alkaline to phenolphthalein with sodium hydroxide (d = 1.33).The base which separates is extracted with chloroform (50 cc). The chloroform solution is dried over anhydrous sodium sulfate and then evaporated to dryness. There are obtained 5-[3-(4-β-hydroxyethylpiperazino)propyl]dibenzazepine (7.95g), the dihydrochloride of which, crystallized from ethanol, melts at about 210°C.

• Therapeutic Function

  Antidepressant, Antipsychotic

OPIPRAMOL Upstream-Materialien And Downstream Produkte

4-(3-(5H-Dibenz(b,f)azepin-5-yl)propyl)-1-piperazinethanol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(68)Suppliers

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