1,3-Dithian

Bezeichnung:1,3-Dithian

CAS-Nr505-23-7

Englisch Name:1,3-Dithiane

CBNumberCB6223805

SummenformelC4H8S2

Molgewicht120.24

MOL-Datei505-23-7.mol

Synonyma

1,3-Dithian

1,3-Dithian physikalisch-chemischer Eigenschaften

Schmelzpunkt	52-54 °C (lit.)
Siedepunkt	207-208°C
Dichte	1.062 (estimate)
Brechungsindex	1.5981 (estimate)
Flammpunkt	195 °F
storage temp.	Inert atmosphere,Room Temperature
Aggregatzustand	Crystals, Needles or Powder
pka	31(at 25℃)
Farbe	White to pale beige
Geruch (Odor)	at 0.01 % in propylene glycol. alliaceous roasted
Geruchsart	alliaceous
Wasserlöslichkeit	Soluble in benzene, ether, chloroform and terahydrofuran. Slightly soluble in water.
Sensitive	Hygroscopic
BRN	102534
InChIKey	WQADWIOXOXRPLN-UHFFFAOYSA-N
LogP	1.729 (est)
CAS Datenbank	505-23-7(CAS DataBase Reference)
NIST chemische Informationen	1,3-Dithiane(505-23-7)

Sicherheit

R-Sätze:	20/21/22
S-Sätze:	22-24/25
RIDADR	UN 1325 4.1/PG 2
WGK Germany	3
RTECS-Nr.	JO5070000
F	13
HazardClass	4.1
PackingGroup	III
HS Code	29349990

Gefahreninformationscode (GHS)

1,3-Dithiane Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white to pale beige crystals, needles or powder
Verwenden
1,3-Dithiane is used in umpolung reactions such as the Corey-Seebach reaction. It acts as a reagent for the deoxygenation of sulfoxides to their corresponding sulfides. Further, it is used as a protecting group for carbonyl compounds used in organic synthesis. It serves as a useful labeled synthon. In addition to this, it is used in the preparation of 2-ethyl-[1,3]dithiane.
Definition
ChEBI: 1,3-dithiane is a dithiane.
Reaktionen
1,3-dithiane has 2 weakly acidic protons that can be removed and alkylation of the carbon is possible. Once alkylated, the 1,3-dithiane becomes a “protected” carbonyl as it can be hydrolyzed to the corresponding carbonyl structure. Alternatively, the 1,3-dithiane moiety may also be introduced by thioacetalisation of a carbonyl group, either using acid or Lewis acid catalysis, 12 or of a 1,1-dihalide (using transition metal catalysis).
Synthesis Reference(s)
Tetrahedron Letters, 29, p. 4477, 1988 DOI: 10.1016/S0040-4039(00)80527-4
Allgemeine Beschreibung
1,3-Dithiane, a protected formaldehyde anion equivalent, serves as useful labeled synthon.
läuterung methode
Crystallise the 1,3-dithiane from 1.5 times its weight of MeOH at 0o, and sublime it at 40-50o/0.1mm. [Groel & Seebach Synthesis 357 1977, Beilstein 19/1 V 13.]

1,3-Dithiane Upstream-Materialien And Downstream Produkte

1,3-Dithian Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

505-23-7, 1,3-Dithiane Verwandte Suche:

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