3,4-Dihydro-2(1H)isochinolin-carbonsäureimidamidsulfat (2:1)

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

DEBRISOQUIN SULFATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R22:Gesundheitsschädlich beim Verschlucken.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

• Chemische Eigenschaften

  Crystalline Solid

• Originator

  Declinax,Roche,UK,1967

• Verwenden

  Antihypertensive.

• Manufacturing Process

  27 g of 1,2,3,4-tetrahydroisoquinoline was added at room temperature to a solution of 28 g of 2-methyl-2-isothiourea sulfate in 80 ml of water. The resulting mixture was kept at room temperature with occasional shaking. After a short period of time, methylmercaptan began to escape, and the mixture warmed up slightly. After then standing for 24 hours, crystals formed. They were filtered off and rinsed with ice cold water. Recrystallization from approximately 100 ml of water yielded 1,2,3,4-tetrahydroisoquinoline-2- carboxamidine sulfate melting at 278°C to 280°C (uncorr.).
  Another batch prepared in the same manner melted at 284°C to 285°C due to a minute difference in moisture content.
  Both batches prepared above analyzed correctly for (C10H13N3)2·H2SO4.

• Trademarks

  Declinax (HoffmannLaRoche).

• Therapeutic Function

  Antihypertensive

• Biochem/physiol Actions

  Debrisoquine is an anti-hypertensive agent. It is metabolized by cytochrome P4502D6.

DEBRISOQUIN SULFATE Upstream-Materialien And Downstream Produkte

3,4-Dihydro-2(1H)isochinolin-carbonsäureimidamidsulfat (2:1) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(34)Suppliers

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